Pink-pigmented facultative methylotrophs (PPFMs) in the genera Methylobacterium and Methylorubrum are highly abundant members of the plant microbiome that have indicated benefits through application to food crops. Several inherent characteristics make PPFMs difficult to successfully ferment and to process into stable forms for production and distribution into agricultural channels. This paper focuses on some of the ways in which NewLeaf Symbiotics has utilized a deep expertise in PPFMs to successfully manufacture and apply them. It details some ways in which formulations can enable the successful application of PPFMs by adding functional materials such as surfactants and film-forming polymers. This paper discusses a case study of using in-furrow and seed treatment application methods in the corn market.