Journal Published Online: 01 January 1982
Volume 27, Issue 1

Applicability of Capillary Gas Chromatography to Substance Identification in Toxicology by Means of Retention Indices

CODEN: JFSCAS

Abstract

Three capillary columns, set up in a routine screening system, were tested in temperature-programmed runs. A narrow-bore fused silica capillary, Carbowax deactivated and with a methylsilicone liquid phase, was found to be unstable at higher temperatures, giving irreproducible results and retention indices that varied considerably from those obtained on packed columns. The two other columns, a wide-bore glass capillary and a narrow-bore fused silica capillary, were polysiloxane-deactivated and had a dimethylpolysiloxane liquid phase. Although both showed good stability, reproducibility, and load capacity, retention indices for various drugs still showed discrepancies as compared to corresponding values on packed columns.

Author Information

Schepers, P
State University, Groningen, The Netherlands
Wijsbeek, J
State University, Groningen, The Netherlands
Franke, JP
State University, Groningen, The Netherlands
de Zeeuw, RA
State University, Groningen, The Netherlands
Pages: 12
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Stock #: JFS11450J
ISSN: 0022-1198
DOI: 10.1520/JFS11450J