ISSN: 0022-1198
CODEN: JFSCA
Published Online: 1 May 1998
Page Count: 4

Greek Cypriot Allele and Genotype Frequencies for Amplitype® PM-DQA1 and D1S80 Loci
Karagrigoriou, A
Associate professor, University of Cyprus,

Budowle, B
Unit Chief, Forensic Science Research and Training Center, FBI Academy, VA

Bashiardes, E
Director, DNA ID Lab, biologist, visiting student, molecular biologist, Cyprus Institute of Neurology and Genetics, DNA Identification Laboratory,

Cariolou, MA
Director, DNA ID Lab, biologist, visiting student, molecular biologist, Cyprus Institute of Neurology and Genetics, DNA Identification Laboratory,

Christophorou, M
Director, DNA ID Lab, biologist, visiting student, molecular biologist, Cyprus Institute of Neurology and Genetics, DNA Identification Laboratory,

Manoli, P
Director, DNA ID Lab, biologist, visiting student, molecular biologist, Cyprus Institute of Neurology and Genetics, DNA Identification Laboratory,

(Received 30 May 1997; accepted 13 October 1997)

Abstract

A sample from the Greek Cypriot population was typed at seven forensically important PCR-based loci: LDLR, GYPA, HBGG, D7S8, GC, HLA-DQA1, and D1S80. The results showed that all loci meet Hardy-Weinberg expectations and that there is no evidence for association of alleles between loci. Allelic frequency distributions at all loci, except HLA-DQA1 and two D1S80 alleles, were similar to those of U.S. Caucasians. Greek Cypriot population databases have been created and can be used for forensic analyses to estimate the frequency of a multiple locus DNA profile.

Keywords:
forensic science, DNA typing, Cyprus, LDLR, HBGG, GYPA, D7S8, GC, HLA-DQA1, D1S80, population genetics, polymerase chain reaction

Paper ID: JFS16199J
DOI: 10.1520/JFS16199J
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