ISSN: 0022-1198
CODEN: JFSCA
Page Count: 3

Fixed Bin Frequency Distributions for the VNTR Locus D5S110 in General United States Reference Databases
Giusti, AM
Program Manager for DNA Research, and Chemist, Forensic Science Research and Training Center, FBI Academy, VA

Budowle, B
Program Manager for DNA Research, and Chemist, Forensic Science Research and Training Center, FBI Academy, VA

(Received 15 April 1994; accepted 11 July 1994)

Abstract

Fixed bin frequencies for the D5S110 locus were determined in African Americans, Caucasians, Southeastern Hispanics, and Southwestern Hispanics. The data were generated by RFLP analysis of HAE III-digested genomic DNA. The D5S110 locus met Hardy-Weinberg expectations in the four sample populations, and there is no evidence for association of alleles between the D5S110 and other routinely used VNTR loci. The frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in various general United States populations.

Keywords:
forensic science, VNTR, allele frequency, population databases, D5S110, equilibrium, RFLP

Paper ID: JFS15348J
DOI: 10.1520/JFS15348J
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