Analysis of the HUMTH01 Allele Frequencies in the Spanish Population

    Volume 39, Issue 5 (September 1994)

    ISSN: 0022-1198

    CODEN: JFSOAD

    Page Count: 5


    Budowle, B
    Program Manager of D.N.A. Research, and S.A., Forensic Science Research and Training Center, Laboratory Division, FBI Academy, Quantico, VA

    Villanueva, E
    Associate Professor, Assistant Professor, and Chairman, University of Granada, Granada,

    Lorente, JA
    Associate Professor, Assistant Professor, and Chairman, University of Granada, Granada,

    Wilson, MR
    Program Manager of D.N.A. Research, and S.A., Forensic Science Research and Training Center, Laboratory Division, FBI Academy, Quantico, VA

    Lorente, M
    Associate Professor, Assistant Professor, and Chairman, University of Granada, Granada,

    (Received 9 July 1993; accepted 7 March 1994)

    Abstract

    Genetic marker typing based on DNA amplification by the polymerase chain reaction (PCR) increasingly is being employed in forensic casework and for paternity testing. The allele frequencies were determined using PCR for 120 unrelated Spanish Caucasians for the locus HUMTH0H1. Six alleles were observed, with frequencies ranging from 0.013 (allele 11) to 0.254 (allele 10). The observed heterozygosity was 75.8%, and the power of discrimination is 0.92. The genotype distribution meets Hardy-Weinberg expectations.


    Paper ID: JFS13712J

    DOI: 10.1520/JFS13712J

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    Title Analysis of the HUMTH01 Allele Frequencies in the Spanish Population
    Symposium , 0000-00-00
    Committee E30