Volume 30, Issue 1 (January 1985)

    Fatal Malignant Hyperthermia as a Result of Ingestion of Tranylcypromine (Parnate®) Combined with White Wine and Cheese

    (Received 30 April 1984; accepted 21 June 1984)

    Published Online: January

    CODEN: JFSOAD

      Format Pages Price  
    PDF 4 $25   ADD TO CART


    Abstract

    Fatal malignant hyperthermia occurred in a patient who was taking tranylcypromine (Parnate®) and ingested wine and cheese. The case findings are presented along with a review of the literature concerning adverse interactions between monoamine oxidase (MAO) inhibitors and certain foods and beverages. Hyperthermia and its possible causative mechanisms and treatments are discussed. The facts suggest that the complicated dietary restrictions attending the use of MAO inhibitors and the possibility of severe and even catastrophic reactions resulting from violations of these restrictions make the use of these drugs fraught with danger and therefore not a first choice for the treatment of depression.


    Author Information:

    Mirchandani, H
    Deputy chief medical examiner and resident in forensic pathology, Wayne County Medical Examiner's Office, Detroit, MI

    Reich, LE
    Deputy chief medical examiner and resident in forensic pathology, Wayne County Medical Examiner's Office, Detroit, MI


    Stock #: JFS10984J

    ISSN: 0022-1198

    DOI: 10.1520/JFS10984J

    ASTM International
    is a member of CrossRef.

    Author
    Title Fatal Malignant Hyperthermia as a Result of Ingestion of Tranylcypromine (Parnate®) Combined with White Wine and Cheese
    Symposium , 0000-00-00
    Committee E30