Volume 22, Issue 1 (January 1977)
Electron Impact Mass Spectrometric Detection of Freon® in Biological Specimens
Recently the toxicity and abuse of aerosols containing Freon® have been brought to the attention of the public. Unpublished reports by the Drug Abuse Council indicate increased instances of aerosol addiction among the very poor, disenfranchised, and marginal minority groups. Also, deaths related to aerosols have been known for years. Bass  described 110 SSDs (Sudden Sniffing Deaths) during the 1960s, 59 of which were Freon-related. Christopoulos and Kirch  and Baselt and Cravey  demonstrated the presence of trichlorofluoromethane and dichlorodifluoromethane in postmortem specimens of Freon-induced deaths. The above authors used gas chromatographic (GC) techniques employing electron capture and flame ionization detectors (FID), respectively, for the quantitative analyses of these compounds. Standefer  also reported FID-GC data on specimens from a death associated with fluorocarbon inhalation.