Work Item
ASTM WK72274

New Test Method for Printability of Bioinks for Extrusion-based Bioprinting

1. Scope

The scope of the Committee shall be the development of standardized nomenclature and definitions of terms, test methods, recommended practices, guides, specifications and performance standards for medical and surgical materials and devices. The Committee will encourage research in this field and sponsor symposia, workshops and publications to facilitate the development of such standards. The Committee will promote liaison with other ASTM Committees and other organizations with mutual interests.

Keywords

bioprinting; bioinks; 3D printing

Rationale

Ballot Rationale The field of bioprinting is a subset of additive manufacturing that is rapidly expanding to meet the needs of the regenerative medicine and tissue engineering community. Bioprinting, together with 3D imaging approaches, can be used to assemble combinations of biomaterials and cells with controlled composition, geometry, and structural integrity. It is a way to synthesize organs and tissues for applications within reconstructive medicine, tissue engineering and drug testing. As an rapidly developing industry, there are a plethora of manufacturers and academic researchers developing bioinks, the substance that is deposited or extruded by a 3D bioprinter. There is a currently a lack of standardization for bioink properties resulting in issues with reproducibility that may slow clinical implementation of this technology. This draft standard describes a test method to measure printability of bioinks made of any material, with or without living cells or biologics, when using an extrusion based bioprinter. Extrusion based bioprinters are the most commonly used machines at this time. The test method is meant to facilitate advancements in bioprinting through standardization and future round robin testing of a wide range of bioinks so that comparisons can be readily and uniformly made between materials and machines.

The title and scope are in draft form and are under development within this ASTM Committee.

Details

Developed by Subcommittee: F04.42

Committee: F04

Staff Manager: Kathleen Chalfin

Work Item Status

Date Initiated: 03-13-2020

Technical Contact: Liisa Kuhn

Item: 001

Ballot: F04.42 (20-01)

Status: Will Reballot Item

Item: 001

Ballot: F04.42 (20-02)

Status: Will Reballot Item