Integrated Pest Management (IPM) has long been a concept embraced by biologists in academia and government, but often the theory of IPM has outpaced the reality of private-sector technology development. Times have now changed and the private sector has developed the vision and products to enable IPM using biological, chemical, and cultural practices. In this paper, we explore the success and continued challenges of developing delivery systems (including formulations) that improve the regulatory profile, expand the performance, minimize off-target effects, and create positive supply-side economics for the manufacturer. Indeed, the changing face of agricultural production, regulation, and competition has created the perfect opportunity—right now—to reinvent our product profiles and raise the bar. The regulatory paradigm that only actives will be of concern has changed in most parts of the world and now must be a consideration with the composition of most products. Precision delivery of actives, irrespective of their formulation, also may enable the utility of older molecules to be rejuvenated and expanded. All of these uncertainties provide risks, but for the wise, also present opportunities to extend the value of older technology with proprietary approaches and to ensure newer technologies see a long life in IPM systems.