SYMPOSIA PAPER Published: 01 January 1965
STP43782S

Studies On Polymer Implants In Humans

Source

The clinical, gross and microscopic findings in cases of plastic implantation in humans for vascular prosthesis and for plastic surgery have been reviewed. Reactions to the following materials are included: Cellophane, Dacron, Nylon, Orlon, polyethylene, and Teflon. The plastic implants are associated with varying intensities of inflammatory reaction and fibrosis. The principal causes of functional failure are thrombosis, hemorrhage, and excessive fibrosis. At times the hemorrhage can be shown to be due to fragmentation of the plastic with loss of mechanical integrity. No specific or characteristic inflammatory lesions were found to be due to any particular plastic. None of the tissues showed evidence of malignant changes.

Author Information

Johnson, F., B.
Armed Forces Institute of Pathology, Washington, D.C.
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Details
Developed by Committee: F04
Pages: 102–104
DOI: 10.1520/STP43782S
ISBN-EB: 978-0-8031-6010-1
ISBN-13: 978-0-8031-6164-1