SYMPOSIA PAPER Published: 01 January 1988

Synthetic Environments for the Testing of Metallic Biomaterials


Synthetic environments used for testing biomaterials are considered. In terms of the environment they seek to simulate, these can be subdivided into saliva substitutes and body fluid substitutes. In respect of the former, it is seen that most formulations used in the past cannot even be taken into solution. In both cases, evidence is presented to suggest that use of electrochemical corrosion test methods or in-vivo use of the same methods gives results that are in error because of simultaneous anodic oxidation of organic species, such as simple redox-type amino acids. The correlation between in-vivo and in-vitro corrosion rates is examined. Agreement is far from satisfactory in many cases.

Author Information

Kuhn, AT
Faculty of Science and Technology, Harrow College of Higher Education, Harrow, United Kingdom
Neufeld, P
Polytechnic of the South Bank, London, United Kingdom
Rae, T
Orthopaedic Research Unit, University of Cambridge, Addenbrookes Hospital, Cambridge, United Kingdom
Price: $25.00
Contact Sales
Reprints and Permissions
Reprints and copyright permissions can be requested through the
Copyright Clearance Center
Developed by Committee: G01
Pages: 79–97
DOI: 10.1520/STP26001S
ISBN-EB: 978-0-8031-5042-3
ISBN-13: 978-0-8031-0977-3