SYMPOSIA PAPER Published: 01 January 1991

Headspace Screening/Capillary Column GC/MS Analysis for Volatile Organics: Validation Studies and Applications


The use of a headspace sampling device coupled with a gas chromatograph/mass spectrometer (GC/MS) equiped with a very large bore capillary column allows the rapid characterization of sample constituents. The MS detector operated in the full scan mode provides adequate sensitivity as well as excellent specificity. Most of the compounds on the volatile target compound list are amenable to analysis using the headspace technique and information on sample constituents not in the analytical standard is available through library searches. The use of the MS as a detector reduces the requirement for chromatographic separation.

Author Information

Flynn, LR
CompuChem Laboratories, Research Triangle Park, N.C.
Bass, SW
CompuChem Laboratories, Research Triangle Park, N.C.
Meierer, RE
CompuChem Laboratories, Research Triangle Park, N.C.
Price: $25.00
Contact Sales
Reprints and Permissions
Reprints and copyright permissions can be requested through the
Copyright Clearance Center
Developed by Committee: D18
Pages: 106–114
DOI: 10.1520/STP25471S
ISBN-EB: 978-0-8031-5159-8
ISBN-13: 978-0-8031-1294-0