Bioactive calcium phosphate materials were developed by Driskell and his co-workers at Battelle Memorial Institute's Columbus Laboratories and successfully implanted At the U. S. Army Institute of Dental Research at Walter Reed Army Medical Center. in 1971. Coatings of these materials were applied to dental implants in 1972. Disappointment with results of earlier research and development of “bioinert” ceramic implant materials and coatings stimulated this departure into bioactive materials development. Subsequent work by Hubbard Jarcho, Kay, and numerous other researchers resulted in the development of additional variations of calcium phosphate materials and coatings. The substance of this research is the foundation upon which the field of calcium phosphate materials technology and hydroxlapatite coatings has developed.
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