SYMPOSIA PAPER Published: 01 January 1987

Application of Computerized Quantitative Infrared Spectroscopy to the Determination of the Principal Lipids Found in Blood Serum


This paper discusses the issues related to the development of a practical infrared spectroscopic method for the determination of the principal types of serum lipids, triglycerides, cholesteryl esters, and phospholipids. Earlier papers on this subject are noted, and the various matrix mathematical approaches used previously for this application are compared. The results described in this work were obtained with a least squares curve fitting type of algorithm, termed a Q-matrix approach. Comparisons are made between results obtained with a number of different methods constructed for use with the Q-matrix approach.

Author Information

McClure, GL
Perkin-Elmer, Corp, Norwalk, CT
Roush, PB
Perkin-Elmer, Corp, Norwalk, CT
Williams, JF
Perkin-Elmer, Corp, Norwalk, CT
Lehmann, CA
School of Applied Health Professions, State University of New York, Stony Brook, NY
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Developed by Committee: E13
Pages: 131–154
DOI: 10.1520/STP23166S
ISBN-EB: 978-0-8031-5001-0
ISBN-13: 978-0-8031-0929-2