From the numerous and diverse studies of pollution effects on marine molluscs, a few species and techniques have emerged as suitable for routine effluent toxicity measurement. As marine mollusc toxicity testing evolves from research to routine application, it has become increasingly important to determine the reliability and repeatability of toxicity measurement, and to evaluate the degree of protection that regulations based on such measures provide for organisms that inhabit receiving waters. This paper reviews recent studies of standard mollusc protocols to estimate their inter- and intralaboratory precision, relative sensitivity, and the degree to which they currently meet proposed criteria for toxicity tests that can be used effectively in regulating effluent discharges.
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