Work Item
ASTM WK73068

New Practice for Determining Antiviral Efficacy of Apparel Textiles Treated with Antimicrobial Agents Intended for the Reduction of Infectious Viral Titer using a Defined SARS-CoV-2 Surrogate

1. Scope

1. Scope 1.1 This practice is used to evaluate the antiviral efficacy of antimicrobial agents applied to textiles with the intention of reducing the infectious viral titer over time. This practice defines a protocol that uses one of several possible SARS-CoV-2 Surrogate viruses and cell lines outlined in the ASTM Guidance document xxxx-2020. 1.2 To determine the virucidal activity of textiles treated with active antimicrobial agent(s), samples of treated and untreated materials are inoculated with a defined viral suspension and then incubated. The changes in numbers of the infectious viral particles on the treated article are compared directly with untreated articles over designated time periods. 1.3 This practice is used for measuring the quantitative antiviral activity of porous textiles that have been treated with a biocide to reduce the survivability of viruses on the treated materials. 1.4 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. 1.5 This method shall be performed by individuals experienced and adept in microbiological and virological techniques and in facilities designed and equipped for work with infectious agents at the appropriate biosafety level. 1.6 It is the responsibility of the investigator to determine whether Good Laboratory Practice regulations (GLPs) are required and to follow them were appropriate (40 CFR, Part 160 for EPA submissions and 21 CFR, Part 58 for FDA submissions). Refer to the appropriate regulatory agency for performance standards of virucidal efficacy for treated textiles. 1.7 This standard may involve hazardous materials, operations, and equipment. This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.


Antiviral; textile; antimicrobial


The standard is currently needed in the textile industry as no current method exists that accurately measures the ability of an apparel textile to reduce the viral load on a textile surface without altering the textile itself. This standard specifically outlines an exposure scenario currently recognized within the textile industry and uses at test system recently recommended as a SARS-CoV-2 surrogate system.

The title and scope are in draft form and are under development within this ASTM Committee.


Developed by Subcommittee: E35.15

Committee: E35

Staff Manager: Brian Milewski

Work Item Status

Date Initiated: 05-17-2020

Technical Contact: Robert Monticello

Item: 000