Journal Published Online: 19 July 2022
Volume 50, Issue 5

Preliminary Investigation of Magnesium-Silver Nanocomposite for Feasibility as Degradable Biomaterial



Pure magnesium is a well-studied metallic material for biodegradable implants, but its rapid degradation rate is a major disadvantage. Silver is known for its excellent antimicrobial and anti-inflammatory properties, but its hemolytic and cytotoxic properties are a major concern. In the presented study, to control the fast degradation rate of magnesium, silver nanoparticles (NPs) were mixed with magnesium in varying proportions. Magnesium-silver composites have been prepared using powder metallurgy techniques with three different proportions of silver Viz. 0.75 %, 1 %, and 1.25 % silver. For the suitability of a composite as an implant material, corrosion rate, hemolysis, and antibacterial activity were investigated with pure magnesium as the control. Pure magnesium shows a corrosion rate of around 5 mm/year, while magnesium-silver composites show around 1.2 mm/year. Zone of inhibition and hemolysis values are higher for magnesium-1.25 % silver when compared with other specimens. Magnesium-0.75 % silver has hemolysis and antibacterial activity similar to pure magnesium, with a lower value of corrosion rate. Silver NPs on their own are hemolytic and cytotoxic, but Magnesium-silver nanocomposites with a silver wt % lower than 1.25 % can be further explored as a suitable biomaterial with reduced corrosion rate and better biocompatibility.

Author Information

Vignesh, R.
Department of Manufacturing Engineering College of Engineering, Anna University, Guindy, Chennai, India
Velusamy, Raja
Department of Manufacturing Engineering, College of Engineering Guindy, Anna University Chennai, Chennai, India
Pages: 9
Price: $25.00
Reprints and Permissions
Reprints and copyright permissions can be requested through the
Copyright Clearance Center
Stock #: JTE20220102
ISSN: 0090-3973
DOI: 10.1520/JTE20220102