Journal Published Online: 01 May 2000
Volume 45, Issue 3

Geographic Origin Determination of Heroin and Cocaine Using Site-Specific Isotopic Ratio Deuterium NMR

CODEN: JFSCAS

Abstract

SNIF-NMR® (Site-specific natural isotopic fractionation measured by deuterium NMR) was employed on 36 heroin samples from seven different known origins, and two cocaine samples from two different known origins. Heroin has two “synthetic” deuterium labeled sites (the two acetyls from acetic anhydride, each representing three equivalent nuclei) and 15 “natural” deuterium labeled sites (originating from the morphine produced in the opium plant). The “natural” sites have the potential for determining geographic location of the original opium plant, while the “synthetic” sites could assist in giving information about the commercial source of acetic anhydride used to convert morphine to heroin. Cocaine has 15 “natural” deuterium labeled sites. This study shows that SNIF-NMR® has some use in determining the geographic origin of heroin and also has good potential for determining the geographical origin of cocaine.

Author Information

Hays, PA
U.S. Drug Enforcement Administration, Special Testing and Research Laboratory, McLean, VA
Remaud, GS
Eurofins Laboratories, rue Pierre Adolphe Bobierre, Site de la Géraudière, Nantes Cedex 3, France
Jamin, É
Eurofins Laboratories, rue Pierre Adolphe Bobierre, Site de la Géraudière, Nantes Cedex 3, France
Martin, Y-L
Eurofins Laboratories, rue Pierre Adolphe Bobierre, Site de la Géraudière, Nantes Cedex 3, France
Pages: 11
Price: $25.00
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Details
Stock #: JFS14728J
ISSN: 0022-1198
DOI: 10.1520/JFS14728J