Journal Published Online: 01 January 2000
Volume 45, Issue 1

Interferences with Semen Detection by an Immunoassay for a Seminal Vesicle-Specific Antigen



A commercial enzyme-linked immunosorbent assay (ELISA), the SEMA® assay, for a seminal vesicle-specific antigen (SVSA) provides highly sensitive detection of semen. Here we show marked interference of proteins such as albumin, serum proteins, or mucin with the assay. This would substantially decrease the sensitivity for detecting semen mixed with other biological fluids such as blood or vaginal secretions.

Author Information

Chen, JT
National Institutes of Health, Bethesda, MD
Hortin, GL
National Institutes of Health, Bethesda, MD
Pages: 2
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Stock #: JFS14670J
ISSN: 0022-1198
DOI: 10.1520/JFS14670J