Journal Published Online: 01 May 1997
Volume 42, Issue 3

Italian Population Allele and Genotype Frequencies for the AmpliType® PM and the HLA-DQ-alpha Loci



The distribution of six genetic loci analyzed by PCR using the commercial AmpliType® PM (PolyMarker) kit (Perkin Elmer, Norwalk, CT) was evaluated in 200 unrelated Italian individuals. The examined loci included: Group-specific component (Gc) (1), D7S8 (2), hemoglobin G gammaglobin (HBGG) (3), glycophorin A (GYPA) (4), low density lipoprotein receptor (LDLR) (5), and HLA DQ-alpha (6). The AmpliType PM Kit analysis is based on the reverse dot blot format and the results are interpreted by reading the pattern of blue dots which determine the alleles present at each locus. The population data collected allow the implementation of AmpliType PM into routine casework.

Author Information

Spinella, A
Biological Unit, Italy
Marsala, P
Biological Unit, Italy
Biondo, R
Biological Unit, Italy
Montagna, P
Biological Unit, Italy
Pages: 5
Price: $25.00
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Stock #: JFS14159J
ISSN: 0022-1198
DOI: 10.1520/JFS14159J