Journal Published Online: 01 March 1997
Volume 42, Issue 2

An Indoor Air Quality-Pharmacokinetic Simulation of Passive Inhalation of Marijuana Smoke and the Resultant Buildup of 11-Nor-Delta-9-Tetrahydrocannabinol-9-Carboxylic Acid in Urine

CODEN: JFSCAS

Abstract

In military courts of law, the good soldier defense is often used by the defendant to explain the presence of 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid in urine (hereafter referred to as THCA) above the Department of Defense (DOD) established limit of 15 ng/mL. The defense will contend the defendant unwittingly breathed side-stream marijuana smoke, thus resulting in the presence of THCA in the defendant's urine. The purpose of this work was to link an indoor air quality model (IAQ) with a pharmacokinetic (PK) model to predict a passive marijuana smoker's resultant concentration of the major urinary metabolite THCA.

Author Information

Giardino, NJ
Armstrong Laboratory, Occupational Environmental Medicine and Health, Brooks Air Force Base, San Antonio, TX
Pages: 3
Price: $25.00
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Stock #: JFS14121J
ISSN: 0022-1198
DOI: 10.1520/JFS14121J