Journal Published Online: 01 November 1988
Volume 33, Issue 6

Chromatographic and Spectroscopic Profiles of of Different Origins: Part I

CODEN: JFSCAS

Abstract

High-resolution capillary gas chromatography with flame ionization detection and mass spectrometry (GC and GC/MS) and high-performance liquid chromatography (HPLC) were used to establish complex chemical profiles (chemical signatures) of Cannabis samples of known origin. Over 100 compounds could be differentiated, including noncannabinoids (terpenes, alkanes) as well as minor and major cannabinoids and their acids. A characteristic peak pattern was found within a limited number of specimens of identical origin. Correlation studies on the basis of peak area ratios [A(x)/A(i.s.)] showed the feasibility of tracing Cannabis chemically to its country of origin. Several forensic science applications for the chromatographic and spectroscopic profiles of confiscated Cannabis samples are discussed, such as detection of additives (phencyclidine), differentiation of chemotypes, and monitoring of tetrahydrocannabinol (THC) potency.

Author Information

Brenneisen, R
Institute of Pharmacy, University of Berne, Berne, MS, Switzerland
ElSohly, MA
ElSohly Laboratories, Inc., Oxford, MS
Pages: 20
Price: $25.00
Related
Reprints and Permissions
Reprints and copyright permissions can be requested through the
Copyright Clearance Center
Details
Stock #: JFS12583J
ISSN: 0022-1198
DOI: 10.1520/JFS12583J