Forensic restriction fragment length polymorphism analyses typically provide two results for each sample, one result for each unique allele, at each genetic locus probed. In collaboration with the member laboratories of the Technical Working Group for DNA Analysis Methods, we have developed graphical techniques that compactly summarize even large numbers of such paired measurements. This paper provides a detailed description of the basic tool, a modified bivariate control chart for data from one sample at one locus. We demonstrate how various modifications and combinations of these “single-locus charts” can be used for within- and among-laboratory quality assurance activities.
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