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    Medical Applications of Titanium and Its Alloys: The Material and Biological Issues

    Brown SA, Lemons JE
    Published: 1996

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    The first key reference source of its kind to feature current information on biomedical applications for titanium and beta-titanium alloys.

    30 comprehensive peer-reviewed papers from leading experts in the field have been divided into 7 major categories:

    Processing and TI 6Al 4V -- 3 papers address the effects of titanium manufacturing and processing, with a particular focus on TI 6Al 4V.

    New Alloys -- The distinct properties and advantages of several new titanium alloys are discussed in 5 papers.

    Porous Coatings -- 3 papers focus on issues pertaining to the mechanical properties of porous coatings.

    Corrosion, Laboratory Studies -- The basic principles of corrosion of titanium and its alloys are explored in four papers.

    Fretting and Wear Testing -- 5 papers present the results of laboratory studies on fretting corrosion and wear of titanium.

    Biological Issues -- Various biological responses to titanium are presented in six papers.

    Clinical Experience -- Clinical experience with such procedures as total hip and knee replacement are among the studies included in 4 papers.

    Important reference volume for industry professionals involved with the research, development, marketing and management of surgical implant devices; government personnel in related research and regulatory capacities; metallurgy and materials science researchers, and university professors and researchers in the biomedical implantfield.

    Table of Contents

    Titanium Alloys as Implant Materials

    Manufacturing Processes for Semi-Finished Titanium Biomedical Alloys

    Taguchi Experiment on the Mechanical Properties of Sintered Titanium 6-4

    New Titanium Alloys to be Considered for Medical Implants

    Characterization of Ti-15Mo Beta Titanium Alloy for Orthopaedic Implant Applications

    Microstructure and Properties of a New Beta Titanium Alloy, Ti-12Mo-6Zr-2Fe, Developed for Surgical Implants

    Optimization of Properties of Ti-15Mo-2.8Nb-3Al-0.2Si & Ti-15Mo-2.8Nb-0.2Si-.260 Beta Titanium Alloys for Application in Prosthetic Implants

    Mechanical and Tribological Properties and Biocompatibility of Diffusion Hardened Ti-13Nb-13Zr — A New Titanium Alloy for Surgical Implants

    Methods of Detecting and Predicting Microfracture in Titanium

    Evaluation of the Corrosion Fatigue Behavior of Porous Coated Ti-6Al-4V

    A Novel Porous Coating Geometry to Improve the Fatigue Strength of Ti-6Al-4V Implant Alloy

    Chemical and Electrochemical Aspects of the Biocompatibility of Titanium and its Alloys

    Passive Dissolution of Titanium in Biological Environments

    Corrosion Behavior of Dental Casting Alloys Coupled with Titanium

    Titanium Oxide Film Fracture and Repassivation: The Effect of Potential, pH and Aeration

    Transitional Behavior in Ti-6Al-4v Fretting Corrosion

    Effects of Material Combination, Surface Treatment, and Environment on Fretting Corrosion of Ti 6Al 4V

    Mechanical and Corrosion Properties of Nitrogen Diffusion Hardened Ti-6Al-4V Alloy

    Characterizing the Fretting Fatigue Behavior of Ti-6Al-4V in Modular Joints

    Wear of Titanium 6-4 Alloy in Laboratory Tests and in Retrieved Human Joint Replacements

    The In Vitro Response to Participate Titanium Alloy

    Response of Titanium Surfaces to Simulated Biological Environments

    In Vitro Osteoblast Responses to cpTi and Ti-6Al-4V Alloy

    Induction of Bone Resorbing Agents by Titanium Particulates: Responses of Macrophages, Fibroblasts and Osteoblasts In Vitro

    Determination of In Vivo Titanium Release from a Non-Articulating Commercially Pure Titanium Implant

    Distribution of Titanium and Vanadium Salts and Corrosion Products in Cells, Fluids, and Organs in vivo and in Cell Culture in vitro

    Clinical Studies on Titanium and Stainless Steel Plates (LC-DCP). A Comparative Evaluation

    Wear and Osteolysis in Relation to Prostheses Design and Materials

    A 3-Year Prospective Study of Serum Titanium Levels in Patients with Primary Total Hip Replacements

    Retrieval Analysis of Ti-6Al-4V Miller-Galante Total Knee Replacements

    Committee: F04

    DOI: 10.1520/STP1272-EB

    ISBN-EB: 978-0-8031-5330-1

    ISBN-13: 978-0-8031-2010-5