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A programmable data base, capable of generating complex application programs with management personnel, was investigated in order to facilitate the documentation requirements of Good Laboratory Practice Standards (GLPS). Emphasis was placed on developing a system that would be adaptable at the small independent laboratory level, that is, one that was limited in funds available for computerization and without high-level programming expertise. A successful system was developed around an enhanced IBM PC (XT) with the following software: the Sensible Solution relational data base, Volkswriter 3.0 word processor, and the Labcode-QC statistical quality control system. Application programs were developed as part of a total sample and data tracking system that featured distinct data categories: laboratory/field collection preparation methods or both; sample batch history; sample inventory listing; laboratory homogenization methods; chemical preparation methods; instrumental methods; final reports and other documents; current sample status; chemical, stock, and standard catalogue; control material catalogue; instrument service log; instrument/equipment calibration; personnel monthly time tracking. The system was developed easily without the expertise of experienced programmers and can be modified readily when needed.
data base, management, Good Laboratory Practice Standards, microprocessor, computerization, data, relational, sample tracking, laboratory, application program, calibration
Research chemist, Columbia National Fisheries Research Laboratory, U.S. Fish and Wildlife Service, Columbia, MO