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Gram-negative bacteria contain endotoxins as integral components of their outer membrane. Endotoxins are potent biological agents, and, as contaminants of dusts, can be associated with acute lung reactivity in exposed individuals. Endotoxins can be quantified in bulk materials, dusts and waters, yet many questions remain to be resolved related to their relative toxicities and other properties.
endotoxin, gram-negative bacteria, agriculture, humidifier fever, Limulus
ChiefAdjunct Professor, National Institute for Occupational Safety and HealthWest Virginia University Health Sciences Center, MorgantownMorgantown, WVWV