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    Nutritional Status and Oxidants

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    This review examines the relationship between vitamin C, vitamin E, selenium, copper, zinc, and other dietary antioxidants and the so-called antioxidant defense systems of the lung. The effects of severe caloric and protein malnutrition and vitamin B-6 deficiency on lung development will also be reviewed. The animal models of oxidant-induced injury discussed include those for paraquat, ozone, nitrogen dioxide, and oxygen toxicity, as well as selected experiments with in vitro systems. Susceptible human populations at risk for oxidant-induced lung damage by virtue of nutritional deficiencies are identified and discussed.


    nutrition, oxidants, vitamin E, vitamin C, selenium, copper, zinc, lung, paraquat

    Author Information:

    Last, JA
    Professor of internal medicine, School of Medicine and Toxic Substances Program, LEHR Facility, University of California, Davis, CA

    Committee/Subcommittee: D22.03

    DOI: 10.1520/STP22835S