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Since the implementation of Section 4 (testing chemical substances and mixtures) of the Toxic Substances Control Act (TSCA), the U.S. Environmental Protection Agency (EPA) has received numerous environmental effects, chemical fate, or health effects testing recommendations for several hundred chemicals. This paper provides information on the types and numbers of Federal Register (FR) notices that EPA has published in response to these testing recommendations. In addition, this paper provides detailed discussions of the chemicals and tests for which chemical fate testing has been conducted under TSCA Section 4 and the methods used to conduct those tests. As of 31 December 1988, 182 TSCA Section 4 FR notices (including 65 TSCA Section 4 FR notices mentioning chemical fate testing, and 15 TSCA Section 4 FR notices requesting chemical fate testing) had been published by EPA in response to numerous testing recommendations. For the 51 chemicals in the 15 TSCA Section 4 FR notices requesting chemical fate testing, test data for 105 of the requested 120 chemical fate tests had been received by 31 December 1988. The 28 test methods used for the 105 chemical fate tests were evaluated; modifications were proposed for a few test methods to improve test data reliability.
chemical fate, biodegradation, photolysis, water solubility, Toxic Substances Control Act
Senior Scientist, Office of Toxic Substances (TS-778), U.S. Environmental Protection Agency, Washington, DC