SYMPOSIA PAPER Published: 01 January 1986
STP17316S

Bioassay for Testing Protective Glove Performance Against Skin Absorption of Organic Solvents

Source

Solvents were administered into closed skin depots on guinea pigs, and the resulting blood concentrations were measured in samples repeatedly withdrawn through a catheter in the carotid artery. The exposure areas were protected with glove membranes of different kinds. Results from experiments with three solvents and various gloves are presented. The authors conclude that this animal model seems suitable for screening purposes and is capable of discerning between various commercial products.

Author Information

Boman, A
National Board of Occupational Safety and Health, Solna, Sweden
Wahlberg, JE
National Board of Occupational Safety and Health, Solna, Sweden Karolinska Hospital, Stockholm, Sweden
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Details
Developed by Committee: F23
Pages: 214–220
DOI: 10.1520/STP17316S
ISBN-EB: 978-0-8031-4967-0
ISBN-13: 978-0-8031-0461-7