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Knowledge of endocrine control of the complex larval developmental processes in insects (metamorphosis) has led to the introduction of insect hormones and their analogues as insecticides known as insect growth regulators (IGRs) with the largest group being juvenile hormone analogues (JHAs). Developmental and metabolic alterations in estuarine crustacean larvae induced by JHAs suggest that these compounds may be interfering with an endocrine system using JH-like compounds. These responses of crustacean larvae during the metamorphic process can be used in the development of biomarkers for the environmental impact of these types of compounds and other potential endocrine disrupting chemicals on estuarine biota.
crustacean larvae, crustacean metamorphosis, endocrinology, endocrine disrupting chemicals, juvenile hormone analogs, energy metabolism
Research Aquatic Biologist, U.S. EPA, National Health & Environmental Effects Research Laboratory, Gulf Breeze, FL