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Denatonium Benzoate (DB), an extremely bitter lignocaine derivative, has been used world wide as an alcohol denaturant for over 30 years. Recent recognition of its application for deterring ingestion of potentially toxic products has led to its introduction as an inert ingredient in pesticides, automotive chemicals and household goods. To determine the applicability of DB use in particular formulations, a standard research protocol has been developed. This assures compatibility, stability and optimum DB concentration to effect a bitter taste in the formulated product. This paper discusses compatibility issues, presents data on product stability and the use of human subjects for taste trials.
denatonium benzoate, bittering agent, poison prevention, ingestion deterrent, taste trial, pesticide poisoning
New Product Development Manager, Macfarlan Smith Ltd., Edinburgh,
President, Tracy Chemical Co., Vancouver, Washington