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    Volume 49, Issue 6 (March 2021)

    Evaluation of Antimicrobial, Antioxidant, and Cytotoxicity Activities of CuO Nanopellets Synthesized by Surfactant-Free Hydrothermal Method

    (Received 25 August 2020; accepted 9 October 2020)

    Published Online: 16 March 2021

    CODEN: JTEVAB

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    Abstract

    Copper oxide nanopellets (CONPs) were produced by hydrothermal strategy. The particles were characterized by distinctive techniques. The synthesized particles were found to have pellet morphology with nonuniform thickness and varying sizes extending between 200 and 550 nm. Studies revealed their microbial nature against both Gram-positive and Gram-negative microscopic organisms, specifically Staphylococcus aureus, Bacillus subtilis, Pseudomonas fluorescens, and Escherichia coli and a plant parasitic pathogen Fusarium oxysporum. Studies demonstrated the antioxidant ability of CONPs at higher concentrations. In this paper, cytotoxicity was measured by blood hemolysis. Anticancer activity of CONPs tested against PC-3, HCT116, A549 and MDA-MB-231 cell lines after 24 hours exhibited IC50 values of 72.27, 144.2, 173.9, and 13.07 μg/mL, respectively. Although these phenomena have been determined in other reports, this report is indeed of significance for CONPs within the particle length of 200–550 nm.

    Author Information:

    Sathyananda, H. M.
    Centre for Research and Evaluation, Bharathiar University, Coimbatore, Tamilnadu

    Department of Chemistry, Sir M. Visvesvaraya Institute of Technology, Bengaluru, Karnataka

    Visvesvaraya Technological University, Jnana Sangama, Belagavi, Karnataka

    Prashanth, P. A.
    Centre for Research and Evaluation, Bharathiar University, Coimbatore, Tamilnadu

    Visvesvaraya Technological University, Jnana Sangama, Belagavi, Karnataka

    Department of Chemistry, PES College of Engineering, Mandya, Karnataka

    Prashanth, G. K.
    Department of Chemistry, Sir M. Visvesvaraya Institute of Technology, Bengaluru, Karnataka

    Visvesvaraya Technological University, Jnana Sangama, Belagavi, Karnataka

    Nagabhushana, B. M.
    Visvesvaraya Technological University, Jnana Sangama, Belagavi, Karnataka

    Department of Chemistry, M. S. Ramaiah Institute of Technology, Bengaluru, Karnataka

    Krishnaiah, G. M.
    Department of Chemistry, Sir M. Visvesvaraya Institute of Technology, Bengaluru, Karnataka

    Visvesvaraya Technological University, Jnana Sangama, Belagavi, Karnataka

    Nagendra, H. G.
    Visvesvaraya Technological University, Jnana Sangama, Belagavi, Karnataka

    Department of Bio-Technology, Sir M. Visvesvaraya Institute of Technology, Bengaluru, Karnataka

    Dileep, M. S.
    Visvesvaraya Technological University, Jnana Sangama, Belagavi, Karnataka

    Department of Physics, Sir M. Visvesvaraya Institute of Technology, Bengaluru, Karnataka

    Ananda, S.
    Department of Chemistry, University of Mysore, Mysuru, Karnataka

    Boselin Prabhu, S. R.
    Department of Electronics and Communication Engineering, Surya Engineering College, Erode, Tamilnadu


    Stock #: JTE20200538

    ISSN:0090-3973

    DOI: 10.1520/JTE20200538

    Author
    Title Evaluation of Antimicrobial, Antioxidant, and Cytotoxicity Activities of CuO Nanopellets Synthesized by Surfactant-Free Hydrothermal Method
    Symposium ,
    Committee B05