Journal Published Online: 01 May 2001
Volume 47, Issue 3

Online Y-chromosomal Short Tandem Repeat Haplotype Reference Database (YHRD) for U.S. Populations

CODEN: JFSCAS

Abstract

We describe here an online Y-chromosomal short tandem repeat haplotype reference database (YHRD) for U.S. populations, which represents 9-locus Y-STR haplotypes for 1705 African-Americans, European-Americans and Hispanics as of October 2001. This database is available online (http://www.ystr. org/usa/), free to access and was generated in order to supply the U.S. forensic DNA community with a valuable resource for frequencies of complete or incomplete 9-locus Y-STR haplotypes, as well as information about typing protocols and population genetic analyses. Pairwise RST-statistics derived from the Y-STR haplotypes indicate no significant substructure among African-American populations from different regions of the U.S., nor (usually) among European-American and Hispanic populations. Thus, pooling of YSTR haplotype data from regional populations within these three major groups is appropriate in order to obtain larger sample sizes. However, pooling of different major populations is generally not recommended due to statistically significant differences between African-American populations and all European-American / Hispanic populations, as well as between some European-American and Hispanic populations.

Author Information

Kayser, M
Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Brauer, S
Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Willuweit, S
Institute for Legal Medicine, Humboldt-University Berlin, Berlin, Germany
Schädlich, H
Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Batzer, MA
Louisiana State University, Baton Rouge, LA
Zawacki, J
Office of Chief Medical Examiner, New York City, NY
Prinz, M
Office of Chief Medical Examiner, New York City, NY
Roewer, L
Institute for Legal Medicine, Humboldt-University Berlin, Berlin, Germany
Stoneking, M
Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Pages: 7
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Stock #: JFS15290J
ISSN: 0022-1198
DOI: 10.1520/JFS15290J