Journal Published Online: 01 May 2001
Volume 46, Issue 3

A New Triplex STR System Without Irregular Alleles by Silver Staining and Its Potential Application to Forensic Analysis

CODEN: JFSCAS

Abstract

In order to increase the discriminating power of DNA analysis in forensic science, we devised a new triplex STR system using three novel STR loci we previously reported, D14S299 (wg1c5), D15S233 (wg1d1), and 9q2h2. We designated this system a CDH triplex system. The CDH triplex system showed a high discriminating power, especially in Caucasians. This system is composed of three STR loci showing only regular tetranucleotide repeat alleles. We easily enlarged the databases mainly of Japanese, using this system, and compared them with those of Caucasian and Chinese. This CDH triplex system therefore appears to be useful for forensic practice.

Author Information

Yoshimoto, T
Postgraduate School of Medicine, Nagoya University, Nagoya, Japan
Yamamoto, T
Postgraduate School of Medicine, Nagoya University, Nagoya, Japan
Uchihi, R
Postgraduate School of Medicine, Nagoya University, Nagoya, Japan
Tamaki, K
Sapporo Medical University School of Medicine, Chuoku, Sapporo, Japan
Huang, X-L
Tokai University School of Medicine, Bohseidai Isehara, Japan
Mizutani, M
Postgraduate School of Medicine, Nagoya University, Nagoya, Japan
Tanaka, M
Postgraduate School of Medicine, Nagoya University, Nagoya, Japan
Armour, JAL
School of Clinical Laboratory Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK
Katsumata, Y
Postgraduate School of Medicine, Nagoya University, Nagoya, Japan
Pages: 5
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Stock #: JFS14995J
ISSN: 0022-1198
DOI: 10.1520/JFS14995J