Journal Published Online: 01 September 1994
Volume 39, Issue 5

Analysis of the HUMTH01 Allele Frequencies in the Spanish Population

CODEN: JFSCAS

Abstract

Genetic marker typing based on DNA amplification by the polymerase chain reaction (PCR) increasingly is being employed in forensic casework and for paternity testing. The allele frequencies were determined using PCR for 120 unrelated Spanish Caucasians for the locus HUMTH0H1. Six alleles were observed, with frequencies ranging from 0.013 (allele 11) to 0.254 (allele 10). The observed heterozygosity was 75.8%, and the power of discrimination is 0.92. The genotype distribution meets Hardy-Weinberg expectations.

Author Information

Lorente, JA
University of Granada, Granada, Spain
Lorente, M
University of Granada, Granada, Spain
Budowle, B
Forensic Science Research and Training Center, Laboratory Division, FBI Academy, Quantico, VA
Wilson, MR
Forensic Science Research and Training Center, Laboratory Division, FBI Academy, Quantico, VA
Villanueva, E
University of Granada, Granada, Spain
Pages: 5
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Stock #: JFS13712J
ISSN: 0022-1198
DOI: 10.1520/JFS13712J