Journal Published Online: 01 July 1993
Volume 38, Issue 4

Identification of Human DNA in Complex Biological Samples Using the Alu Polymerase Chain Reaction

CODEN: JFSCAS

Abstract

Alu-Polymerase chain reaction (PCR) was used to amplify human DNA from complex mixed sources of DNA. Amplification of human DNA sequences by Alu-PCR could be accomplished in samples containing low concentrations of template in the presence of excess heterologous DNA sequences. Thus, sensitivity and specificity are maintained in complex DNA mixtures allowing positive identification of the presence of human DNA sequences by this technique.

Author Information

Tsongalis, GJ
University of North Carolina, Chapel Hill, N.C.
Coleman, WB
University of North Carolina, Chapel Hill, N.C.
Esch, GL
University of North Carolina, Chapel Hill, N.C.
Smith, GJ
University of North Carolina, Chapel Hill, N.C.
Kaufman, DG
University of North Carolina, Chapel Hill, N.C.
Pages: 7
Price: $25.00
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Stock #: JFS13495J
ISSN: 0022-1198
DOI: 10.1520/JFS13495J