Journal Published Online: 01 July 1993
Volume 38, Issue 4

The Development of DNA Profiling Database in an HAE III Based RFLP System for Chinese, Malays, and Indians in Singapore

CODEN: JFSCAS

Abstract

Deoxyribonucleic acid (DNA) restriction fragment length polymorphism (RFLP) profiles were obtained for blood specimens from the three population groups—Chinese, Malays and Indians—in Singapore. The population databases were collected from Hae III digested high molecular weight DNA hybridized with four variable number of tandem repeats (VNTR) loci - D2S44, D10S28, D4S139 and D1S7. The data were analyzed statistically using the fixed bin system. Comparison of ratio of bin frequencies of these population data with published data on whites, blacks, and hispanics shows that the alleleic distribution at these loci is not seriously different among the six groups. This has important implications to the statistical significance of forensic DNA applications.

Author Information

Chow, ST
Institute of Science and Forensic Medicine, Singapore
Tan, WF
Institute of Science and Forensic Medicine, Singapore
Yap, KH
Institute of Science and Forensic Medicine, Singapore
Ng, TL
Institute of Science and Forensic Medicine, Singapore
Pages: 11
Price: $25.00
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Stock #: JFS13484J
ISSN: 0022-1198
DOI: 10.1520/JFS13484J