Journal Published Online: 01 May 1990
Volume 35, Issue 3

Lithium-Ammonia Reduction of Ephedrine to Methamphetamine: An Unusual Clandestine Synthesis

CODEN: JFSCAS

Abstract

A suspected clandestine methamphetamine laboratory was seized in Vacaville, California. Ephedrine, a precursor for the manufacture of methamphetamine, was discovered at the site. However, the chemicals normally expected to be found at an ephedrine conversion laboratory were not recovered. Other chemicals found at the scene included tetrahydrofuran, ammonium chloride, lithium metal, and ammonia gas. Examination of the suspect's notes showed several different common synthesis routes to methamphetamine and a novel route utilizing a lithium/ammonia/ammonium chloride reduction. The reduction of ephedrine to methamphetamine using this dissolving metal procedure has not been reported in the literature. The authors reproduced the suspect's reaction scheme and found the lithium/ammonia/ammonium chloride reduction of ephedrine to be a viable synthesis for methamphetamine.

Author Information

Ely, RA
U.S. Drug Enforcement Administration, Western Laboratory, San Francisco, CA
McGrath, DC
U.S. Drug Enforcement Administration, Western Laboratory, San Francisco, CA
Pages: 4
Price: $25.00
Related
Reprints and Permissions
Reprints and copyright permissions can be requested through the
Copyright Clearance Center
Details
Stock #: JFS12878J
ISSN: 0022-1198
DOI: 10.1520/JFS12878J