Journal Published Online: 01 January 1990
Volume 35, Issue 1

An Improved Method for Complement Subcomponent C1R Typing

CODEN: JFSCAS

Abstract

An improved method has been developed for the reliable classification of different C1R genetic variant forms from human serum or plasma. The method combines the use of neuraminidase-digested samples followed by monodimensional isoelectric focusing in the pH range 5 to 8 followed by immunoblotting. The method yields a simple pattern, with one major band in homozygote and two major bands in heterozygote cases.

Author Information

Kamboh, MI
Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA
Ferrell, RE
Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA
Pages: 3
Price: $25.00
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Stock #: JFS12817J
ISSN: 0022-1198
DOI: 10.1520/JFS12817J