Journal Published Online: 01 November 1989
Volume 34, Issue 6

Fatal Accidental Enflurane Intoxication

CODEN: JFSCAS

Abstract

Among reported cases of abuse of volatile anesthetics there is only one of enflurane intoxication. We report another fatal enflurance intoxication. A 21-year-old man found dead seemed to have experimented with enflurane. Three and one-half days after death high amounts of enflurane were detected in blood, brain, and subcutaneous fat. Gas chromatographic quantification revealed the following high enflurane concentrations: blood: 130 mg/l−1, brain: 350 mg/l−1, and subcutaneous fat: 100 mg/l−1. Histologic signs of drug-induced damage were lacking. No suicide intentions became known. It was concluded that the young man died of an accidental intoxication while abusing enflurane.

Author Information

Jacob, B
Heinrich-Heine-University Düsseldorf, Düsseldorf, West Germany
Heller, C
Heinrich-Heine-University Düsseldorf, Düsseldorf, West Germany
Daldrup, T
Heinrich-Heine-University Düsseldorf, Düsseldorf, West Germany
Bürrig, KF
Heinrich-Heine-University Düsseldorf, Düsseldorf, West Germany
Barz, J
Heinrich-Heine-University Düsseldorf, Düsseldorf, West Germany
Bonte, W
Heinrich-Heine-University Düsseldorf, Düsseldorf, West Germany
Pages: 5
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Stock #: JFS12783J
ISSN: 0022-1198
DOI: 10.1520/JFS12783J