Journal Published Online: 01 November 1989
Volume 34, Issue 6

Inactivation of Human Immunodeficiency Virus (HIV) by Ionizing Radiation in Body Fluids and Serological Evidence

CODEN: JFSCAS

Abstract

A method to use ionizing radiation to inactivate HIV (Human Immunodeficiency Virus) in human body fluids was studied in an effort to reduce the risk of accidental infection to forensic science laboratory workers. Experiments conducted indicate that an X-ray absorbed dose of 25 krad was required to completely inactivate HIV. This does not alter forensically important constituents such as enzymes and proteins in body fluids. This method of inactivation of HIV cannot be used on body fluids which will be subjected to deoxyribonucleic acid (DNA) typing.

Author Information

Bigbee, PD
Forensic Science Research and Training Center, FBI Laboratory, FBI Academy, Quantico, VA
Sarin, PS
Laboratory of Tumor Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD
Humphreys, JC
Ionizing Radiation Division, National Institute of Standards and Technology, Gaithersburg, MD
Eubanks, WG
Scientific Analysis Section, FBI Laboratory, Washington, DC
Sun, D
Laboratory of Tumor Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD
Hocken, DG
Ionizing Radiation Division, National Institute of Standards and Technology, Gaithersburg, MD
Thornton, A
Laboratory of Tumor Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD
Adams, DE
Scientific Analysis Section, FBI Laboratory, Washington, DC
Simic, MG
Ionizing Radiation Division, National Institute of Standards and Technology, Gaithersburg, MD
Pages: 8
Price: $25.00
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Stock #: JFS12770J
ISSN: 0022-1198
DOI: 10.1520/JFS12770J