Journal Published Online: 01 July 1988
Volume 33, Issue 4

The Identification of Nitromethaqualone and Its Differentiation from Some Positional Isomers

CODEN: JFSCAS

Abstract

Nitromethaqualone [2-methyl-3(2′-methoxy-4′-nitrophenyl)-4(3H)-quinazolinone] and its three positional isomers formed by moving the nitro group on the phenyl ring containing the 2′-methoxyl group have been synthesized and characterized. Mass spectra, infrared spectra, nuclear magnetic resonance spectra, and the gas-liquid chromatographic behavior of these compounds are presented. It is shown that infrared spectroscopy, nuclear magnetic resonance spectroscopy, and electron impact mass spectroscopy combined with gas-liquid chromatography are capable of differentiating nitromethaqualone from any of the studied isomers, methaqualone, and mecloqualone.

Author Information

Clark, CC
Drug Enforcement Administration, Southeast Laboratory, Miami, FL
Pages: 10
Price: $25.00
Related
Reprints and Permissions
Reprints and copyright permissions can be requested through the
Copyright Clearance Center
Details
Stock #: JFS12528J
ISSN: 0022-1198
DOI: 10.1520/JFS12528J