Journal Published Online: 01 April 1986
Volume 31, Issue 2

Profiles of Δ -Tetrahydrocannabinol Metabolites in Urine of Marijuana Users: Preliminary Observations by High Performance Liquid Chromatography-Radioimmunoassay

CODEN: JFSCAS

Abstract

Metabolic profiles of 11-nor-9-carboxylic acid-Δ9-tetrahydrocannabinol (COOH-THC) and other THC metabolites were determined in an infrequent and a frequent marijuana user by high performance liquid chromatography-radioimmunoassay (HPLC-RIA). In the infrequent user, no unconjugated COOH-THC was detected in urine samples for the first 8 h following smoking, whereas this metabolite was detected in the urine samples from a frequent user. A metabolite was also detected in the frequent user, which was not present in the urine sample from the infrequent user.

Author Information

Alburges, ME
University of Utah, Salt Lake City, UT
Peat, MA
Chemical Toxicology, Institute, Foster City, CA
Pages: 12
Price: $25.00
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Stock #: JFS12302J
ISSN: 0022-1198
DOI: 10.1520/JFS12302J