Journal Published Online: 01 July 1982
Volume 27, Issue 3

Analysis of Explosives by Liquid Chromatography-Negative Ion Chemical Ionization Mass Spectrometry

CODEN: JFSCAS

Abstract

On-line high performance liquid chromatography (HPLC)-negative ion chemical ionization (NCI) mass spectrometry has been used for the analysis of explosives mixtures. The liquid chromatography-mass spectrometry (LC/MS) interface used was a commercial direct liquid introduction interface allowing about 1% of the solvent/sample effluent into the ion source. The HPLC mobile phases were acetronitrile/water (50:50) and methanol/water (50:50), which served also as NCI reagent gases. Standard mixtures containing 2,4,6-trinitrotoluene (TNT), cyclonite (RDX), tetryl, and pentaerythritol tetranitrate (PETN), and a military explosive, tetrytol, have been analyzed by the LC/MS system. The minimum detectable amount of TNT was 100 ng injected on column, or approximately 1 ng to the ion source.

Author Information

Parker, CE
Laboratory of Environmental Chemistry, National Institute of Environmental Health Sciences, Research Triangle Park, NC
Voyksner, RD
Laboratory of Environmental Chemistry, National Institute of Environmental Health Sciences, Research Triangle Park, NC University of North Carolina, Chapel Hill
Tondeur, Y
Laboratory of Environmental Chemistry, National Institute of Environmental Health Sciences, Research Triangle Park, NC
Henion, JD
New York State College of Veterinary Medicine, Cornell University, Ithaca
Harvan, DJ
Laboratory of Environmental Chemistry, National Institute of Environmental Health Sciences, Research Triangle Park, NC
Hass, JR
Laboratory of Environmental Chemistry, National Institute of Environmental Health Sciences, Research Triangle Park, NC
Yinon, J
Weizman Institute of Science, Rehovot, NC, Israel
Pages: 11
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Stock #: JFS12161J
ISSN: 0022-1198
DOI: 10.1520/JFS12161J