Journal Published Online: 01 April 1980
Volume 25, Issue 2

The Preparation of -Pseudococaine from -Cocaine

CODEN: JFSCAS

Abstract

d-Pseudococaine, a diastereoisomer of cocaine, is prepared from l-cocaine by the action of strong base that epimerizes the carbomethoxy group at C-2 to the equatorial position and transesterifies the ester at C-3. The benzoate ester is regenerated by reaction with benzoyl chloride. The d-pseudococaine thus prepared is then subjected to a variety of instrumental and analytical techniques to effect its characterization. The tests done are those commonly used in forensic science laboratories for cocaine analysis. With these data, a laboratory can eliminate or confirm pseudococaine in such an analysis.

Author Information

Siegel, JA
Metropolitan State College, Denver, Colo
Cormier, RA
Metropolitan State College, Denver, Colo
Pages: 9
Price: $25.00
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Stock #: JFS12136J
ISSN: 0022-1198
DOI: 10.1520/JFS12136J