Journal Published Online: 01 September 1999
Volume 44, Issue 5

STR HUMARA Locus Gene and Genotype Frequencies in Han and Bei Populations in China

CODEN: JFSCAS

Abstract

For the purpose of the population genetics study of the HUMARA locus, the allele, and genotype frequencies were determined in two Chinese population samples (Han-101, Bei-113) using PCR, PAGE, and silver staining. Fourteen alleles were found. The size of amplified fragments were 258 bp-315 bp. The observed heterozygosities were 0.83 in the Han population and 0.73 in the Bei population respectively. The expected heterozygosities were 0.91 in the Han population and 0.97 in the Bei population respectively. Both populations meet Hardy-Weinberg expectation, Han population x2 = 17.7206, df = 11, p > 0.05; Bei population x2 = 7.4268, df = 10, p > 0.05. The discrimination power were 0.95 in females and 0.89 in males in the Han population, 0.94 in females and 0.88 in males in the Bei population. Thus, the allelic frequency data can be used in the personal identification and parentage testing in the forensic science practice. The PCR test established in this study is robust and reproducible.

Author Information

Wu, MY
West China University of Medical Sciences, Chengdu, P.R. China
Zou, LP
Court of Justice of Yunnan Province, The People's Republic of China
Shen, B
School of Forensic Medicine, Kuming Medical College, The People's Republic of China
Sun, GY
West China University of Medical Sciences, Chengdu, P.R. China
Li, RH
West China University of Medical Sciences, Chengdu, P.R. China
Chen, GD
West China University of Medical Sciences, Chengdu, P.R. China
Pages: 3
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Stock #: JFS12037J
ISSN: 0022-1198
DOI: 10.1520/JFS12037J