Journal Published Online: 01 January 1984
Volume 29, Issue 1

Differentiation of Side Chain Positional Isomers of Amphetamine

CODEN: JFSCAS

Abstract

The eleven side chain positional isomers of amphetamine can be distinguished using a combination of color tests, thin-layer chromatography, and mass spectrometry. The primary amines, 1-phenylpropylamine and β-methylphenethylamine, exhibited chromatographic behavior similar to amphetamine but were readily differentiated using mass spectrometry. The mass spectra of N-methylphenethylamine was very similar to amphetamine, but using color tests and chromatography it was readily differentiated from amphetamine.

Author Information

Soine, WH
School of Pharmacy Medical College of Virginia/Virginia Commonwealth University, Richmond, VA
Thomas, MN
School of Pharmacy Medical College of Virginia/Virginia Commonwealth University, Richmond, VA
Shark, RE
Drug Examination Section, Bureau of Forensic Science, Consolidated Laboratories of Virginia, Richmond, VA
Scott, J
Drug Examination Section, Bureau of Forensic Science, Consolidated Laboratories of Virginia, Richmond, VA
Agee, DT
Drug Examination Section, Bureau of Forensic Science, Consolidated Laboratories of Virginia, Richmond, VA
Pages: 8
Price: $25.00
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Stock #: JFS11649J
ISSN: 0022-1198
DOI: 10.1520/JFS11649J