Journal Published Online: 01 October 1983
Volume 28, Issue 4

Drugs and Driving: A Systematic Analytical Approach

CODEN: JFSCAS

Abstract

To collect useful epidemiological data about drug involvement in highway safety, it is essential that sensitive and specific analytical procedures be used to establish the presence of and to determine the concentrations of drugs and metabolites in samples collected from drivers. This paper describes a comprehensive and systematic screening procedure requiring 6 mL of blood, which has been used for the analysis of samples collected from injured and fatally injured drivers. The procedure uses radioimmunoassay, gas chromatography with selective detectors, and high performance liquid chromatography. Drugs and metabolites presumptively identified are then confirmed primarily using gas chromatography$#x2014;chemical ionization mass spectrometry.

Author Information

Crouch, DJ
Center for Human Toxicologiy, University of Utah, Salt Lake City, UT
Peat, MA
Center for Human Toxicologiy, University of Utah, Salt Lake City, UT
Chinn, DM
Center for Human Toxicologiy, University of Utah, Salt Lake City, UT
Finkle, BS
Center for Human Toxicologiy, University of Utah, Salt Lake City, UT
Pages: 12
Price: $25.00
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Stock #: JFS11603J
ISSN: 0022-1198
DOI: 10.1520/JFS11603J