Journal Published Online: 01 October 1983
Volume 28, Issue 4

The Quantitation of Psilocybin in Hallucinogenic Mushrooms Using High Performance Liquid Chromatography

CODEN: JFSCAS

Abstract

A method using high performance liquid chromatography (HPLC) with an acetonitrile, water, and phosphoric acid mobile phase and a bonded cyano-amino-type polar phase column has been developed for the rapid, selective, and accurate quantitation of psilocybin in dry mushroom material. A simple one-step procedure is used for the quantitative extraction of psilocybin in under 60 min. The 267:254 nm absorbance ratio is used as a check on peak purity for the psilocybin response.

Author Information

Sottolano, SM
Drug Enforcement Administration, Northeast Laboratory, New York, NY
Lurie, IS
Drug Enforcement Administration, Special Testing and Research Laboratory, McLean, VA
Pages: 7
Price: $25.00
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Stock #: JFS11601J
ISSN: 0022-1198
DOI: 10.1520/JFS11601J