Journal Published Online: 01 April 1983
Volume 28, Issue 2

Accidental Digoxin Overdose in an Infant: Postmortem Tissue Concentrations

CODEN: JFSCAS

Abstract

We report the digoxin concentration in various tissues of a seven-week-old infant who died 45 min after receiving an accidental intravenous overdose of digoxin. The digoxin content of various organs was calculated and expressed as a percentage of dose administered. The literature of accidental massive digoxin overdose in infants has been reviewed. Data on tissue concentrations and distribution of digoxin in this age group is scarce. The concentration of digoxin in myocardium, kidney, liver, and other organs observed in our case rank among the highest ever reported in human tissues.

Author Information

Hastreiter, AR
University of Illinois Hospital Medical Center, Chicago, IL
Kim, PW
Mount Prospect, IL
van der Horst, R
University of Illinois Medical Center, Chicago, IL
Pages: 7
Price: $25.00
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Stock #: JFS11532J
ISSN: 0022-1198
DOI: 10.1520/JFS11532J